ZC3H8 antibody

Principal name

ZC3H8 antibody

Alternative names for ZC3H8 antibody

ZC3HDC8, Fliz1, Zinc finger CCCH domain-containing protein 8

SwissProt ID

Q8N5P1 (Human), Q9JJ48 (Mouse)

Gene ID

84524 (ZC3H8), 57432 (Zc3h8)

Available reactivities

Hu (Human), Ms (Mouse), Mky (Monkey), Rt (Rat)

Available hosts

Rabbit, Mouse

Available applications

Enzyme Immunoassay (E), Paraffin Sections (P), Western blot / Immunoblot (WB), Immunocytochemistry/Immunofluorescence (ICC/IF)

Background of ZC3H8 antibody

Acts as a transcriptional repressor of the GATA3 promoter. Sequence-specific DNA-binding factor that binds to the 5'-AGGTCTC-3' sequence within the negative cis-acting element intronic regulatory region (IRR) of the GATA3 gene (By similarity). Induces thymocyte apoptosis when overexpressed, which may indicate a role in regulation of thymocyte homeostasis.

General readings

1, Lamesch, P., et al. Genomics 89(3):307-315(2007).
2. Hwang, E.S., et al. Immunology 106(4):464-469(2002).
3. Hwang, E.S., et al. J. Immunol. 169(1):248-253(2002).

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