ALDH3 antibody

Principal name

ALDH3 antibody

Alternative names for ALDH3 antibody

ALDH3A1, Aldehyde dehydrogenase 3, ALDHIII, Aldehyde dehydrogenase, dimeric NADP-preferring, Aldehyde dehydrogenase family 3 member A1

SwissProt ID

A3RF36 (Canfa), P11883 (Rat), P30838 (Human), P30907 (Bovin), P47739 (Mouse)

Gene ID

218 (ALDH3A1), 25375 (Aldh3a1)

Available reactivities

Hu (Human), Ms (Mouse), Bov (Bovine), Can (Canine), Rt (Rat), Eq (Equine), GP (Guinea Pig), Por (Porcine)

Available hosts

Mouse, Rabbit, Goat

Available applications

Enzyme Immunoassay (E), Western blot / Immunoblot (WB), Paraffin Sections (P), ELISA (detection) (E(detection)), EPair for Elisa (EPair), Immunoprecipitation (IP), Flow Cytometry (F), Immunocytochemistry/Immunofluorescence (ICC/IF)

Background of ALDH3 antibody

Aldh3A1 is a member of the aldehyde dehydrogenase superfamily, a group of NAD(P)(+)-dependent enzymes that catalyze the oxidation of a wide spectrum of aliphatic and aromatic aldehydes. Aldh3A1 is highly expressed in stomach and even more strongly in cornea, representing between 5 to 50% of the water soluble protein fraction in mammalian corneas. It is thought that Aldh3A1 acts to protect the cornea from UV-induced oxidative stress by not only detoxification of reactive aldehydes by also through the direct absorbtion of UV energy. However, corneas from Aldh3A1-null mice are indistinguishable from those from wild-type mice; mice lacking both Aldh3A1 and Aldh1A1 showed increased cataract formation following UVB exposure, suggesting that Aldh1A1 may be able to compensate for the loss of Aldh3A1. At least two isoforms of Aldh3A1 are known to exist. This antibody is predicted to have no cross-reactivity to Aldh3A2.

General readings

Estey T., et al. (2007) Exp Eye Res. 84(1):3-12
Bogucka M., et al. (2009) Acta Pol Pharm. 66(5):477-82.

  1. Filtre rapide:
  2. Validés (2)

2 article(s)

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Anticorps Primaires

N° du Produit Hôte Isotype Clone Presentation Reactivité Applications  

ALDH3 anticorps

  anti-ALDH3A1 mouse monoclonal antibody, clone OTI1B6 (formerly 1B6)  
Immunohistochemical staining of paraffin-embedded pancreas tissue within the normal limits using anti-ALDH3A1 mouse monoclonal antibody. (Heat-induced epitope retrieval by 10mM citric buffer, pH6.0, 100C for 10min, TA501105, Dilution 1:50) Mouse IgG2a OTI1B6 Purified Hu F, ICC/IF, P, WB
0.1 ml / 379,00 €
  OriGene Technologies, Inc.

TrueMAB

ALDH3 anticorps

  anti-ALDH3A1 mouse monoclonal antibody, clone OTI1C6 (formerly 1C6)  
Immunohistochemical staining of paraffin-embedded prostate tissue within the normal limits using anti-ALDH3A1 mouse monoclonal antibody. (Heat-induced epitope retrieval by 10mM citric buffer, pH6.0, 100C for 10min, TA501139, Dilution 1:50) Mouse IgG2a OTI1C6 Purified Hu F, ICC/IF, P, WB
0.1 ml / 350,00 €
  OriGene Technologies, Inc.

TrueMAB

2 article(s)

par Page
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