discontinued

AR10320PU-L Lambda Light Chain

Search for all "Lambda Light Chain"

Vue générale rapide

Lambda Light Chain

AR10320PU-L

Description du Produit Lambda Light Chain

Lambda Light Chain.
Presentation: Purified

Caractéristiques du Produit Lambda Light Chain

Type de Produit Proteins & Growth Factors
Quantité 10 mg
Presentation Purified
Poids Moléculaire 23 kDa
Espèce (Protéine) Human
Destination Worldwide
Fiche Technique Télécharger la fiche technique
Fournisseur Acris Antibodies GmbH
Material Safety DataSheet (MSDS) MSDS for Proteins (de)

Extrait de la Fiche Technique

Pureté > 96.0%
Sujet

Lambda light chain is the smaller of the two types of polypeptide chains in immunoglobulins, consisting of an antigen-binding segment with a variable amino acid sequence, and a constant region with a relatively unchanging amino acid sequence. The lambda light chain gene is located on chromosome 22. The immunoglobulin heavy chains (G, A, M, D, or E) and light chains (kappa or lambda) are produced separately by the plasma cells in the bone marrow. The kappa and lambda molecules are attached to the heavy chains and whole immunoglobulins are assembled, and then conveyed to the surface of the plasma cell. Small amounts of free kappa and lambda light chains are found in the serum of healthy individuals since they are produced in excess. An accurate measurement of serum levels of free light chains in the presence of a great excess of bound light chains has been quite tricky for many years due to their identical structure. A number of diseases affect the production of free light chains by the plasma cells in the bone marrow, causing abnormal levels in the serum, urine or cerebrospinal fluid.
Lambda along with kappa light chains can be used as a tumor marker in urine.

Stockage

Store undiluted at 2 8°C.
Shelf life: one year from despatch.

Source Human Urine
Description
Description:
Human Lambda light chain produced in Human Urine.
Presentation
Buffer:
Lyophilized from 0.02M NH4HCO3
Pureté:
> 96.0%
Format:
Sterile Filtered White lyophilized (freeze-dried) powder
Purified
Reconstitution:
Restore in Sodium Acetate buffer at pH 4.0 containing 0.5M NaCl
  • LinkedIn