AR10745PU-S Enfuvirtide T-20

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Vue générale rapide

Enfuvirtide T-20


Description du Produit Enfuvirtide T-20

Enfuvirtide T-20.
Presentation: Purified

Caractéristiques du Produit Enfuvirtide T-20

Type de Produit Proteins & Growth Factors
Quantité 90 mg
Presentation Purified
Poids Moléculaire 4492
Source Synthetic
Destination Worldwide
Fiche Technique Télécharger la fiche technique
Fournisseur OriGene Technologies GmbH
Material Safety DataSheet (MSDS) MSDS for Proteins (de)

Extrait de la Fiche Technique

Pureté > 99.0% as determined by both RP-HPLC and SDS-PAGE analysis

Enfuvirtide also called human immunodeficiency fusion inhibitor blocks HIV's ability to infect healthy CD4 cells. It can reduce the amount of HIV in the blood and increase the number of CD4 cells. Enfuvirtide operates by disrupting the HIV-1 molecular machinery at the final phase of fusion with the target cell, preventing uninfected cells from becoming infected. Enfuvirtide mimics components of the HIV-1 fusion apparatus and displace them, preventing normal fusion. HIV attaches to the host CD4+ cell receptor using the viral protein GP120; upon binding, GP120 deforms allowing the viral protein GP41 to insert itself into the host cell's plasma membrane. Entry inhibitors bind to GP41 preventing the formation of an entry pore for the capsid of the virus, keeping it out of the cell. 


Prior to reconstitution store at 2-8°C.
Following reconstitution store undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer.
Avoid repeated freezing and thawing.
Shelf life: one year from despatch.

Source Synthetic
Enfuvirtide has an amino acid sequence CH3CO-Tyr-Thr-Ser-Leu-Ile-His-Ser-Leu-Ile-Glu-Glu-Ser-Gln-Asn-Gln-Gln-Glu-Lys-Asn-Glu-Gln-Glu-Leu-Leu-Glu-Leu-Asp-Lys-Trp-Ala-Ser-Leu-Trp-Asn-Trp-Phe-NH2
Molecular formula:
The protein (1 mg/ml) was lyophilized with no additives
> 99.0% as determined by both RP-HPLC and SDS-PAGE analysis
Sterile Filtered White lyophilized (freeze-dried) powder
Restore in sterile 18MΩ-cm-1 H2O not less than 100μg/ml, which can then be further diluted to other aqueous solutions
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