Caractéristiques du Produit SMAD1 Lysate

Type de Produit Lysates
Target Category
Quantité 0.1 mg
Synonymes BSP1, JV4-1, JV41, MADH1, MADR1
Destination Not USA/Canada
Fiche Technique Télécharger la fiche technique
Fournisseur Novus Biologicals Inc.

Extrait de la Fiche Technique

Immunogène
Swiss Prot:
Q15797
Add. information This product is manufactured by and sold under license from OriGene Technologies and its use is limited solely for research purposes.
Research Areas: Lipid and Metabolism
Applications Western Blot, This product is intended for use as a positive control in Western Blot., Western Blot
Sujet The protein encoded by this gene belongs to the SMAD, a family of proteins similar to the gene products of the Drosophila gene 'mothers against decapentaplegic' (Mad) and the C. elegans gene Sma. SMAD proteins are signal transducers and transcriptional modulators that mediate multiple signaling pathways. This protein mediates the signals of the bone morphogenetic proteins (BMPs), which are involved in a range of biological activities including cell growth, apoptosis, morphogenesis, development and immune responses. In response to BMP ligands, this protein can be phosphorylated and activated by the BMP receptor kinase. The phosphorylated form of this protein forms a complex with SMAD4, which is important for its function in the transcription regulation. This protein is a target for SMAD-specific E3 ubiquitin ligases, such as SMURF1 and SMURF2, and undergoes ubiquitination and proteasome-mediated degradation. Alternatively spliced transcript variants encoding the same protein have been observed. [provided by RefSeq]. Transcript Variant: This variant (1) represents the longer transcript. Both variants encode the same protein. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
Concentration 1 mg/ml
Stockage Store at -20C. Avoid freeze-thaw cycles.
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