discontinued

NBP1-49288 TPMT anticorps

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Vue générale rapide

Rabbit anti Human TPMT

Description du Produit TPMT

Rabbit anti Human TPMT.
Presentation: Aff - Purified
Product is tested for Enzyme Immunoassay, Western blot / Immunoblot.

Caractéristiques du Produit TPMT

Type de Produit Anticorps Primaires
Quantité 0.2 mg
Synonymes anti-HGNC:12014antibody, anti-S-adenosyl-L-methionine:thiopurine S-methyltr, anti-TPMT antibody, anti-thiopurine S-methyltransferaseantibody, anti-thiopurine methyltransferase antibody
Presentation Aff - Purified
Reactivité d'Espèce Hu
Applications E, WB
Clonalité Polyclonal
Hôte Rabbit
Isotype IgG
Destination Europe only
Fiche Technique Télécharger la fiche technique
Fournisseur Novus Biologicals Inc.

Extrait de la Fiche Technique

Immunogène
Swiss Prot:
Q9BS45
Immunogène:
Synthetic peptide (KLH-coupled) within residues 200-250 of human TPMT protein (Swiss Prot: P51580)
GeneID:
7172
Sujet This gene encodes the enzyme that metabolizes thiopurine drugs via S-adenosyl-L-methionine as the S-methyl donor and S-adenosyl-L-homocysteine as a byproduct. Thiopurine drugs such as 6-mercaptopurine are used as chemotherapeutic agents. Genetic polymorphisms that affect this enzymatic activity are correlated with variations in sensitivity and toxicity to such drugs within individuals. A pseudogene for this locus is located on chromosome 18q.
Concentration 0.5 mg/ml
Stockage Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Presentation
Purification:
Immunogen affinity purified
Buffer:
PBS, pH 7.4
Format:
Aff - Purified
ID Gène 7172

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