AP06301PU-N H/K/N-Ras anticorps

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0.1 mg / 350,00 €
Please visit the country specific website of OriGene Technologies or contact your local Distributor to buy this product.

Vue générale rapide

Rabbit anti Human, Mouse, Rat H/K/N-Ras

Description du Produit H/K/N-Ras

Rabbit anti Human, Mouse, Rat H/K/N-Ras.
Presentation: Aff - Purified
Product is tested for Western blot / Immunoblot, Paraffin Sections.

Caractéristiques du Produit H/K/N-Ras

Type de Produit Anticorps Primaires
Quantité 0.1 mg
Presentation Aff - Purified
Reactivité d'Espèce Hu, Ms, Rt
Applications P, WB
Clonalité Polyclonal
Hôte Rabbit
Poids Moléculaire ~ 21 kDa
Destination Worldwide
Fiche Technique Télécharger la fiche technique
Fournisseur OriGene Technologies GmbH
Material Safety DataSheet (MSDS) MSDS for Polyclonal Antibodies (de)

Extrait de la Fiche Technique

Immunogène
Immunogène:
Synthetic peptide, corresponding to amino acids 1-50 of Human Ras.
Applications Western blot: 1/500-1/1000.
Immunohistochemistry on paraffin sections: 1/50-1/200.
Sujet The KRAS gene encodes the human cellular homolog of a transforming gene isolated from the Kirsten rat sarcoma virus. The RAS proteins are GDP/GTP-binding proteins that act as intracellular signal transducers. The most well-studied members of the RAS (derived from 'RAt Sarcoma' virus) gene family include KRAS, HRAS, and NRAS. These genes encode immunologically related proteins with a molecular mass of 21 kD and are homologs of rodent sarcoma virus genes that have transforming abilities. While these wildtype cellular proteins in humans play a vital role in normal tissue signaling, including proliferation, differentiation, and senescence, mutated genes are potent oncogenes that play a role in many human cancers.
Concentration 1.0 mg/ml
Stockage Store undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer.
Avoid repeated freezing and thawing.
Shelf life: One year from despatch.
Presentation
Purification:
Affinity Chromatography using epitope-specific immunogen
Buffer:
Phosphate buffered saline (PBS), pH7.2
Agent Conservateur:
0.05% Sodium Azide
Format:
Liquid purified Ig fraction (> 95% pure by SDS-PAGE)
Aff - Purified
Reactivité d'Espèce
Species reactivity (expected):
Mouse and Rat.
Reactivité d'Espèce (Testé):
Human.
Specificité
Specificité:
This antibody detects endogenous levels of RASH/RASK protein.
(region surrounding His27)

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