AP01257PU-N FZD5/FZD8 anticorps

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0.1 mg / 370,00 €
Please visit the country specific website of OriGene Technologies or contact your local Distributor to buy this product.

Vue générale rapide

Rabbit anti Human, Mouse, Rat FZD5/FZD8

Description du Produit FZD5/FZD8

Rabbit anti Human, Mouse, Rat FZD5/FZD8.
Presentation: Aff - Purified
Product is tested for Immunocytochemistry/Immunofluorescence, Enzyme Immunoassay, Western blot / Immunoblot.

Caractéristiques du Produit FZD5/FZD8

Type de Produit Anticorps Primaires
Quantité 0.1 mg
Synonymes Frizzled-5, Frizzled-8
Presentation Aff - Purified
Reactivité d'Espèce Hu, Ms, Rt
Applications E, ICC/IF, WB
Clonalité Polyclonal
Hôte Rabbit
Poids Moléculaire ~ 75 kDa
Destination Worldwide
Fiche Technique Télécharger la fiche technique
Fournisseur OriGene Technologies GmbH
Material Safety DataSheet (MSDS) MSDS for Polyclonal Antibodies (de)

Extrait de la Fiche Technique

Synthetic peptide, corresponding to amino acids 42-90 of Human Frizzled-5.
Applications Western blot: 1/500-1/1000.
Immunofluorescence: 1/50-1/200.
Sujet The frizzled gene, originally identified in Drosophila melanogaster, is involved in the development of tissue polarity. The mammalian homolog of frizzled, as well as several secreted mammalian frizzled-related proteins: FRP-1 (also designated SARP2), FRP-2 (also designated SARP1), FRP-3, FRP-4 and SARP3 (also designated FRP-5), have been identified. The frizzled proteins contain seven transmembrane domains, a cysteine-rich domain in the extracellular region and a carboxy terminal Ser/Thr-xxx-Val motif. They function as receptors for Wnt. The frizzled-1 gene maps to human chromosome 7q21 and is expressed in adult heart, placenta, lung, kidney, pancreas, prostate and ovary and in fetal lung and kidney. Frizzled-2 is expressed in adult heart and fetal brain, lung and kidney. The frizzled related proteins FRP-1, FRP-2, FRP-3, FRP-4 and SARP3 are secreted proteins of approximately 30 kDa that contain regions of homology to the cysteine-rich ligand-binding domain of frizzled and a conserved hydrophilic carboxy terminal.
Concentration 1.0 mg/ml
Stockage Store undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer.
Avoid repeated freezing and thawing.
Shelf life: one year from despatch.
Affinity-chromatography using epitope-specific immunogen
Phosphate buffered saline (PBS)
Agent Conservateur:
0.05% Sodium azide
Liquid purified Ig fraction
Aff - Purified
Reactivité d'Espèce
Species reactivity (expected):
Mouse and Rat.
Reactivité d'Espèce (Testé):
This antibody detects endogenous levels of FZD5 / FZD8 protein (region surrounding Trp73).

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