AM20636PU-N ERK1 / ERK2 anticorps

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0.1 mg / 390,00 €
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Vue générale rapide

Mouse anti Human, Insect, Mouse, Rat, Yeast ERK1 / ERK2 IL-13

AM20636PU-N

Description du Produit ERK1 / ERK2

Mouse anti Human, Insect, Mouse, Rat, Yeast ERK1 / ERK2 IL-13.
Presentation: Purified
Product is tested for Immunocytochemistry/Immunofluorescence, Paraffin Sections, Western blot / Immunoblot.

Caractéristiques du Produit ERK1 / ERK2

Type de Produit Anticorps Primaires
Quantité 0.1 mg
Synonymes ERK-1/ERK-2, MAPK1/MAPK2, P42/P44-MAPK
Presentation Purified
Reactivité d'Espèce Hu, Insect, Ms, Rt, Ye
Applications ICC/IF, P, WB
Clonalité Monoclonal
Clone IL-13
Hôte Mouse
Isotype IgG1
Destination Worldwide
Fiche Technique Télécharger la fiche technique
Fournisseur OriGene Technologies GmbH
Material Safety DataSheet (MSDS) MSDS for Monoclonal Antibodies (de)

Extrait de la Fiche Technique

Isotype Control AM03095PU-N, SM10P (for use in human samples), SM20P (for use in rat samples)
Applications Western Blot: 0.25 - 0.5 μg/ml.
Immunohistochemistry on paraffin sections: 0.4 - 1 μg/ml.
Immunocytochemistry.
Sujet In mammalian cells, a variety of extracellular stimuli generate intracellular signals that converge on a limited number of so-called mitogen-activated protein (MAP) kinase pathways. The central core of each MAP kinase (MAPK) pathway is a conserved cascade of 3 protein kinases: an activated MAPK kinase kinase (MAPKKK) phosphorylates and activates a specific MAPK kinase (MAPKK), which then activates a specific MAPK. Mek1/2 MAPK kinases are essential for mammalian development, homeostasis, and Raf-induced hyperplasia. Germline mutations in genes within the MAPK pathway cause cardio-facio-cutaneous syndrome.
Concentration 0,1 mg/ml (after reconstitution with PBS)
Références Générales
  1. Rodriguez-Viciana P, Tetsu O, Tidyman WE, Estep AL, Conger BA, Cruz MS, et al. Germline mutations in genes within the MAPK pathway cause cardio-facio-cutaneous syndrome. Science. 2006 Mar 3;311(5765):1287-90. Epub 2006 Jan 26. PubMed PMID: 16439621.
  2. Scholl FA, Dumesic PA, Barragan DI, Harada K, Bissonauth V, Charron J, et al. Mek1/2 MAPK kinases are essential for Mammalian development, homeostasis, and Raf-induced hyperplasia. Dev Cell. 2007 Apr;12(4):615-29. PubMed PMID: 17419998.
Stockage Prior to reconstitution store at -20°C.
Following reconstitution store undiluted at 2-8°C for one month
or (in aliquots) at -20°C for longer.
Avoid repeated freezing and thawing.
Shelf life: one year from despatch.
Presentation
Purification:
Affinity chromatography
Buffer:
1.2 % sodium acetate, with 2 mg BSA and 0.01 mg sodium azide as preservative.
Format:
Lyphilized purified Ig fraction
Purified
Reconstitution:
Restore with 1.2% sodium acetate or neutral PBS
Specificité
Specificité:
This antibody reacts to ERK1 / ERK2.
Espèces:
Human, Mouse, Rat, Yeast.

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