TA327291 Cullin 1 anticorps

CUL1 Rabbit Polyclonal Antibody

See related secondary antibodies

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0.1 mg / 335,00 €
Please visit the country specific website of OriGene Technologies or contact your local Distributor to buy this product.

Vue générale rapide

Rabbit anti Human, Mouse, Rat Cullin 1

TA327291

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  • TA327291

Description du Produit Cullin 1

Rabbit anti Human, Mouse, Rat Cullin 1.
Presentation: Purified

Caractéristiques du Produit Cullin 1

Type de Produit Anticorps Primaires
Target Category
Quantité 0.1 mg
Synonymes CUL-1, CUL1, Cullin-1
Presentation Purified
Reactivité d'Espèce Hu, Ms, Rt
Clonalité Polyclonal
Hôte Rabbit
Isotype IgG
Destination Europe, USA/Canada
Fiche Technique Télécharger la fiche technique
Fournisseur OriGene Technologies, Inc.

Extrait de la Fiche Technique

Immunogène
Swiss Prot:
Q13616
Immunogène:
Recombinant protein of human CUL1.
GeneID:
8454
Applications WB 1:500 - 1:2000
IHC 1:50- 1:200
Sujet Ubiquitin can be covalently linked to many cellular proteins by the ubiquitition process, which targets proteins for degradation by the 26S proteasome. Three components are involved in the target protein-ubiquitin conjugation process. Ubiquitin is first activated by forming a thiolester complex with the activation component E1; the activated ubiquitin is subsequently transferred to the ubiquitin-carrier protein E2, then from E2 to ubiquitin ligase E3 for fil delivery to the epsilon-NH2 of the target protein lysine residue. Combitorial interactions of different E2 and E3 proteins result in substrate specificity. Recent data suggest that activated E2 associates transiently with E3, and that the dissociation is a critical step for ubiqitition. Cullin homolog 1 (CUL1), the mammalian homolog of Cdc53 from yeast, is a molecular scaffold of the SCF (Skp1/CUL1/F-box) E3 ubiquitin ligase protein complex. Thus, CUL1 and its family members function in ubiquitin dependent proteolysis. In particular, CUL1 has been shown to mediate ubiquitin dependent degradation of p21 Waf1/Cip1, cyclin D and IkappaB-alpha.
Presentation
Purification:
Affinity purification
Buffer:
Store at -20C or -80C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Format:
Purified

Accessory Products

Protéines et/ou Positive Controls

Protéines pour Cullin 1 (7 produits)

N° du Produit Espèces Presentation Pureté   Source  

Cullin 1

Cullin 1 Human > 80 %
Preparation: Recombint protein was captured through anti-DDK affinity column followed by conventiol chromatography steps.
Purity Detail: > 80% as determined by SDS-PAGE and Coomassie blue staining.
HEK293 cells
20 µg / 680,00 €
  OriGene Technologies, Inc.

Cullin 1 (1-410, His-tag)

Recombinant human CUL1, 1- 410 aa, His-tagged Human Purified > 95 % E. coli
0.25 mg / 750,00 €
  OriGene Technologies GmbH

Cullin 1 (1-410, His-tag)

Recombinant human CUL1, 1- 410 aa, His-tagged Human Purified > 95 % E. coli
50 µg / 300,00 €
  OriGene Technologies GmbH

Cullin 1

Cullin 1 Human Purified 12.5% SDS-PAGE Stained with Coomassie Blue.
  Abnova Taiwan Corp.

Cullin 1

Cullin 1 Human Purified 12.5% SDS-PAGE Stained with Coomassie Blue.
  Abnova Taiwan Corp.

Cullin 1

Cullin 1 Human Purified
  Novus Biologicals Inc.

Cullin 1

Cullin 1 Human Purified
  Novus Biologicals Inc.

Positive Controls pour Cullin 1 (1 produits)

N° du Produit Espèces Presentation Pureté   Source  

Cullin 1 Lysate

Western Blot: Cullin 1 Lysate [NBL1-09606] - Western Blot experiments. 
Left-Control; Right -Over-expression Lysate for CUL1
  Novus Biologicals Inc.
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