AM08398FC-N CD45 anticorps

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Vue générale rapide

Mouse anti Guinea Pig CD45 1H-1

Description du Produit CD45

Mouse anti Guinea Pig CD45 1H-1.
Presentation: FITC
Product is tested for Paraffin Sections, Flow Cytometry.

Caractéristiques du Produit CD45

Type de Produit Anticorps Primaires
Quantité 50 µg
Synonymes CD45R, CD45RA, CD45RB, CD45RO, L-CA, Leukocyte common antigen, PTPRC, T200
Presentation FITC
Reactivité d'Espèce GP
Applications F, P
Clonalité Monoclonal
Clone 1H-1
Hôte Mouse
Isotype IgG1
Destination Worldwide
Fiche Technique Télécharger la fiche technique
Fournisseur OriGene Technologies GmbH
Material Safety DataSheet (MSDS) MSDS for Monoclonal Antibodies (de)

Extrait de la Fiche Technique

Applications Flow Cytometry: Use 10 µl of neat-1/10 diluted antobody to label 10e6 cells in 100 µl.
Immunohistochemistry on Paraffin Sections: 10 µg/ml.
Sujet CD45 is a family of single chain transmembraneous glycoproteins consisting of at least four isoforms (220, 205, 190, 180 kDa) which share a common large intracellular domain. Their extracellular domains are heavily glycosylated. The different isoforms are produced by alternative messenger RNA splicing of three exons of a single gene on chromosome 1. CD45 is expressed on cells of the human hematopoietic lineage (including hematopoietic stem cells) with the exception of mature red cells. It is not detected on differentiated cells of other tissues. It is likely that CD45 plays an important role in signal transduction, inhibition or upregulation of various immunological functions. Antibodies recognising a common epitope on all of the isoforms are termed CD45 whilst those recognising only individual isoforms are termed CD45RA or CD45RO etc.
Références Générales
  1. Hart IJ, Schäfer H, Scheper RJ, Stevenson GT. Subpopulations of guinea-pig T lymphocytes defined by isoforms of the leucocyte common antigen. Immunology. 1992 Nov;77(3):377-84. PubMed PMID: 1362184. (Free PMC Article available)
Stockage Store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer.
This Product is photosensitive and should be protected from light.
Avoid repeated freezing and thawing.
Shelf life: one year from despatch.
Protein A Chromatography.
PBS, pH 8.0 containing 1% BSA as stabilizer and 0.09% Sodium Azide as preservative.
Liquid purified Ig fraction.
Reactivité d'Espèce
Reactivité d'Espèce (Testé):
Guinea Pig.
AM08398FC-N recognizes CD45 on all leucocytes.
Immunoprecipitates proteins of M.Wt. 220,000, 210,000, 195,000 and 180,000 from lymph node lymphocytes and proteins of M.Wt 195,000, 180,000 and 170,000 from thymocytes.

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