AM10038PU-N CD175s anticorps

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1 ml / 360,00 €
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Mouse anti Human CD175s STN219


Description du Produit CD175s

Mouse anti Human CD175s STN219.
Presentation: Purified
Product is tested for Frozen Sections, Immunocytochemistry/Immunofluorescence, Paraffin Sections, Flow Cytometry.

Caractéristiques du Produit CD175s

Type de Produit Anticorps Primaires
Quantité 1 ml
Synonymes NeuAc a GalNAc, Sialosyl Tn, Sialosyl-Tn, Sialyl Tn, sTn
Presentation Purified
Reactivité d'Espèce Hu
Applications C, F, ICC/IF, P
Clonalité Monoclonal
Clone STN219
Hôte Mouse
Isotype IgG1
Destination Worldwide
Fiche Technique Télécharger la fiche technique
Fournisseur Acris Antibodies GmbH
Material Safety DataSheet (MSDS) MSDS for Monoclonal Antibodies (de)

Extrait de la Fiche Technique

Ovine submaxillary mucin (OSM)
Molecular weight of antigen: Several HM weight glycoproteins.
Epitope: NeuAc alphaGalNacOSer/Thr.
Isotype Control AM03095PU-N, SM10P (for use in human samples)
Applications Suitable for Immunohistochemistry and Immunocytochemistry (Frozen or Formalin-Fixed Paraffin-Embedded (FFPE) tissue sections and cell smears)
For IHC dilute concentared antibody at 1/50-1/100, use streptavidin~biotin system or polymer system, incubate 30 minutes at room temperature.
Flow Cytometry.

Recommended Positive Control: Human gastrointestinal tumor, prostate, ovary ca
Sujet Sialosyl Tn antigen also known as CD175s is expressed in the majority of colon, gastric, breast and lung carcinoma.
The sialosyl Tn has limited expression to being absent in normal colon, pancreas, stomach, ovary, and prostate. This antigen is detected in several adenocarcinomas. It appears to be useful marker for poorly differentiated colon adenocarcinomas. This antibody stains colon carcinomas and ovarian mucinous carcinomas producing apical cytoplasmic, apical membrane or luminal staining patterns. It is negative with majority of adult tissue sections.
Concentration 0.2 mg/ml
Références Générales
  1. Gold, DV et. al. Tumor Biol. 9: 137-144, 1990.
  2. Siddiki, B et. al. Intl. J Cancer, 54: 467-474, 1993.
  3. Itzkowitz,S, S et. al. Cancer, 66: 1960-1966, 1990.
  4. Wang, F et. al. J Histochem. Cytochem. 49:1581-1591, 2001.
  5. Ju, T et. al. Cancer Res. 68: 1636-1646, 2008.
  6. Pinho, S, et. al. Cancer Lett. 249: 157, 2006.
Stockage Store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer.
Avoid repeated freezing and thawing.
Shelf life: One year from despatch.
PBS, pH 7.4 containing 1% BSA as stabilizer and 0.05% Sodium Azide as preservative.
Liquid purified Ig fraction.
The specificity of this antibody is similar to B 72.3 antibody.
Cellular Localization: Cytoplasmic, apical membrane, luminal.

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