TA311135 ALDH3 (C-term) anticorps

Goat Anti-ALDH3A1 Antibody

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0.1 mg / 360,00 €
Please visit the country specific website of OriGene Technologies or contact your local Distributor to buy this product.

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Goat anti Human, Mouse ALDH3

TA311135

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  • TA311135

Description du Produit ALDH3

Goat anti Human, Mouse ALDH3.
Properties: (C-term)
Presentation: Aff - Purified
Product is tested for Paraffin Sections, Enzyme Immunoassay, Western blot / Immunoblot.

Caractéristiques du Produit ALDH3

Type de Produit Anticorps Primaires
Target Category
Quantité 0.1 mg
Synonymes ALDH3A1, ALDHIII, Aldehyde dehydrogenase, Aldehyde dehydrogenase 3, Aldehyde dehydrogenase family 3 member A1, dimeric NADP-preferring
Presentation Aff - Purified
Reactivité d'Espèce Hu, Ms
Applications E, P, WB
Clonalité Polyclonal
Hôte Goat
Destination Europe, USA/Canada
Fiche Technique Télécharger la fiche technique
Fournisseur OriGene Technologies, Inc.

Extrait de la Fiche Technique

Immunogène
Swiss Prot:
P47739
Immunogène:
Synthetic peptide from the C Terminus of the protein sequence according to NP_000682.3.
Séquence AA:
C-RYPPSPAKMTQH
Caractéristiques C-term
Add. information Calculated Molecular Weight: 50.5kDa according to Mouse NP_031462.2
Applications Peptide ELISA:  1/32000 (Detection Limit). 
Western blot: 0.01-0.03 µg/ml. Detects a band of Approx 55kDa in Mouse Eye lysates.
Immunohistochemistry on Paraffin Sections: 3-5 µg/ml. In paraffin embedded Human Lung shows strong staining of the respiratory epithelium of the tracheal wall.
Sujet Aldehyde dehydrogenases oxidize various aldehydes to the corresponding acids. They are involved in the detoxification of alcohol-derived acetaldehyde and in the metabolism of corticosteroids, biogenic amines, neurotransmitters, and lipid peroxidation. ALDH3A1 forms a cytoplasmic homodimer that preferentially oxidizes aromatic and medium-chain (6 carbons or more) saturated and unsaturated aldehyde substrates. The enzyme is thought to promote resistance to UV and 4-hydroxy-2-nonenal-induced oxidative damage in the cornea.
Concentration 0.5 mg/ml
Références Générales
  1. Bogucka M, Giebułtowicz J, Zawada K, Wroczyński P, Wierzchowski J, Pietrzak M, et al. The oxidation status of ALDH3A1 in human saliva and its correlation with antioxidant capacity measured by ORAC method. Acta Pol Pharm. 2009 Sep-Oct;66(5):477-82. PubMed PMID: 19894643.
Stockage Store undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer.
Avoid repeated freezing and thawing.
Shelf life: one year from despatch.
Presentation
Purification:
Ammonium Sulphate Precipitation followed by Antigen Affinity Chromatography using the immunizing peptide.
Buffer:
Tris saline, pH~7.3
Agent Conservateur:
0.02% Sodium Azide
Stabilisateurs:
0.5% BSA
Format:
Liquid purified IgG fraction.
Aff - Purified
Reactivité d'Espèce
Species reactivity (expected):
Human.
Reactivité d'Espèce (Testé):
Mouse.
Specificité
Specificité:
Reported variants represent identical protein: NP_001128639.1, NP_000682.3, NP_001128640.1

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