TA306638 ALDH3 anticorps

Rabbit Polyclonal Aldh3A1 Antibody

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0.1 mg / 371,00 €
Please visit the country specific website of OriGene Technologies or contact your local Distributor to buy this product.

Vue générale rapide

Rabbit anti Human, Mouse, Rat ALDH3

Description du Produit ALDH3

Rabbit anti Human, Mouse, Rat ALDH3.
Presentation: Aff - Purified
Product is tested for Enzyme Immunoassay, Western blot / Immunoblot.

Caractéristiques du Produit ALDH3

Type de Produit Anticorps Primaires
Target Category
Quantité 0.1 mg
Synonymes ALDH3A1, ALDHIII, Aldehyde dehydrogenase, Aldehyde dehydrogenase 3, Aldehyde dehydrogenase family 3 member A1, dimeric NADP-preferring
Presentation Aff - Purified
Reactivité d'Espèce Hu, Ms, Rt
Applications E, WB
Clonalité Polyclonal
Hôte Rabbit
Isotype IgG
Destination Europe, USA/Canada
Fiche Technique Télécharger la fiche technique
Fournisseur OriGene Technologies, Inc.

Extrait de la Fiche Technique

Immunogène
Swiss Prot:
P30838
Immunogène:
Aldh3A1 antibody was raised against a 13 amino acid peptide near the carboxy terminus of the human Aldh3A1. (AP30043CP-N)
GeneID:
218
Add. information Blocking peptide available: blocking peptide (AP30043CP-N)
Applications ELISA.
Western Blot: Aldh3A1 antibody can be used for detection of Aldh3A1 at 1 – 2 μg/ml.
Sujet Aldh3A1 is a member of the aldehyde dehydrogenase superfamily, a group of NAD(P)(+)-dependent enzymes that catalyze the oxidation of a wide spectrum of aliphatic and aromatic aldehydes. Aldh3A1 is highly expressed in stomach and even more strongly in cornea, representing between 5 to 50% of the water soluble protein fraction in mammalian corneas. It is thought that Aldh3A1 acts to protect the cornea from UV-induced oxidative stress by not only detoxification of reactive aldehydes by also through the direct absorbtion of UV energy. However, corneas from Aldh3A1-null mice are indistinguishable from those from wild-type mice; mice lacking both Aldh3A1 and Aldh1A1 showed increased cataract formation following UVB exposure, suggesting that Aldh1A1 may be able to compensate for the loss of Aldh3A1. At least two isoforms of Aldh3A1 are known to exist. This antibody is predicted to have no cross-reactivity to Aldh3A2.
Références Générales
  1. Vasiliou V, Pappa A. Polymorphisms of human aldehyde dehydrogenases. Consequences for drug metabolism and disease. Pharmacology. 2000 Sep;61(3):192-8. PubMed PMID: 10971205.
  2. Hsu LC, Chang WC, Shibuya A, Yoshida A. Human stomach aldehyde dehydrogenase cDNA and genomic cloning, primary structure, and expression in Escherichia coli. J Biol Chem. 1992 Feb 15;267(5):3030-7. PubMed PMID: 1737758.
  3. Pappa A, Sophos NA, Vasiliou V. Corneal and stomach expression of aldehyde dehydrogenases: from fish to mammals. Chem Biol Interact. 2001 Jan 30;130-132(1-3):181-91. PubMed PMID: 11306042.
  4. Estey T, Cantore M, Weston PA, Carpenter JF, Petrash JM, Vasiliou V. Mechanisms involved in the protection of UV-induced protein inactivation by the corneal crystallin ALDH3A1. J Biol Chem. 2007 Feb 16;282(7):4382-92. Epub 2006 Dec 11. PubMed PMID: 17158879.
Stockage Store the antibody undiluted at 2-8°C.
Shelf life: one year from despatch.
Presentation
Purification:
Affinity chromatography purified via peptide column
Buffer:
PBS containing 0.02% sodium azide.
Format:
Liquid purified Ig fraction
Aff - Purified
Specificité
Specificité:
This antibody reacts to ALDH3A1.
Espèces:
Human, Mouse, Rat.

Accessory Products

Protéines et/ou Positive Controls

Protéines pour ALDH3 (9 produits)

N° du Produit Espèces Presentation Pureté   Source  

ALDH3 (transcript variant 2)

ALDH3 Human > 80 %
Preparation: Recombint protein was captured through anti-DDK affinity column followed by conventiol chromatography steps.
Purity Detail: > 80% as determined by SDS-PAGE and Coomassie blue staining.
HEK293 cells
20 µg / 438,00 €
  OriGene Technologies, Inc.

ALDH3 (transcript variant 3)

ALDH3 Human > 80 %
Preparation: Recombint protein was captured through anti-DDK affinity column followed by conventiol chromatography steps.
Purity Detail: > 80% as determined by SDS-PAGE and Coomassie blue staining.
HEK293 cells
20 µg / 438,00 €
  OriGene Technologies, Inc.

ALDH3 (transcript variant 1)

ALDH3 Human > 80 %
Preparation: Recombint protein was captured through anti-DDK affinity column followed by conventiol chromatography steps.
Purity Detail: > 80% as determined by SDS-PAGE and Coomassie blue staining.
HEK293 cells
20 µg / 438,00 €
  OriGene Technologies, Inc.

ALDH3 (1-453, His-tag)

ALDH3 Human Purified > 95 % by SDS - PAGE E. coli
0.25 mg / 1 000,00 €
  OriGene Technologies GmbH

ALDH3 (1-453, His-tag)

ALDH3 Human Purified > 95 % by SDS - PAGE E. coli
50 µg / 370,00 €
  OriGene Technologies GmbH

ALDH3

ALDH3 Human Purified 12.5% SDS-PAGE Stained with Coomassie Blue.
  Abnova Taiwan Corp.

ALDH3

ALDH3 Human Purified 12.5% SDS-PAGE Stained with Coomassie Blue.
  Abnova Taiwan Corp.

ALDH3

ALDH3 Human
  Abnova Taiwan Corp.

ALDH3

SDS-Page: ALDH3A1 Protein [NBP1-37091] - ALDH3A1, 52.5 kDa (473aa)  with a purity of 95% by SDS - PAGE
  Novus Biologicals Inc.

Positive Controls pour ALDH3 (4 produits)

N° du Produit Espèces Presentation Pureté   Source  

ALDH3A1 293T Cell Transient Overexpression Lysate(Denatured)

ALDH3A1 293T Cell Transient Overexpression Lysate(Denatured)
  Abnova Taiwan Corp.

ALDH3A1 Lysate

Western Blot: ALDH3A1 Lysate [NBL1-07455] - Western Blot experiments. 
Left-Control; Right -Over-expression Lysate for ALDH3A1 Protein
  Novus Biologicals Inc.

ALDH3A1 overexpression lysate

ALDH3A1 overexpression lysate
0.1 mg / 295,00 €
  OriGene Technologies, Inc.

ALDH3A1 overexpression lysate

ALDH3A1 overexpression lysate
0.1 mg / 295,00 €
  OriGene Technologies, Inc.
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